Bibliography

Abdalla IG, Scorza CA, Cavalheiro EA, de Albuquerque M. Attitudes of Brazilian epileptologists to discussion about SUDEP with their patients: truth may hurt, but does deceit hurt more? Epilepsy Behav 2013;27:470-71.

Adab N, Kini U, Vinten J, Ayres J, Baker G, Clayton-Smith J, et al. The longer term outcomes of children born to mothers with epilepsy. J Neurol Neurosurg & Psych 2004;75:1575-83.

American Clinical Neurophysiology Society. Guideline twelve: guidelines for long-term monitoring for epilepsy. J Clin Neurophysiol 2008;25:170-80.

Ali A, Wu S, Issa NP, Rose S, Towle VL, Warnke P, Tao JX. Association of sleep with sudden unexpected death in epilepsy. Epilepsy Behav 2017;76:1-6.

Anderson JH, Bos JM, Cascino GD, Ackerman MJ. Prevalence and spectrum of electroencephalogram-identified epileptiform activity among patients with long QT syndrome. Heart Rhythm 2014;11:53-57.

Annegers JF. United States perspective on definitions and classifications. Epilepsia 1997;38(Suppl 11):9-12.

Ashby S & Hanna J. Coroners’ rulings on avoidable epilepsy-related deaths. UK: SUDEP Action; 2014.

Auerbach DS, Jones J, Clawson BC, Offord J, Lenk GM, Ogiwara I, et al. Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome. PloS one 2013;8(10):e77843.

Aurlien D, Leren TP, Tauboll E, Gjerstad L. New SCN5A mutation in a SUDEP victim with idiopathic epilepsy. Seizure 2009;18:158-160.

Aurlien D, Larsen JP, Gjerstad L, Taubøll E. Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: a nested, case-control study. Epilepsia 2012;53:258-66.

Badheka A, Rathod A, Kizilbash MA, Lai Z, Mohamad T, Shah A, et al. Epileptic patients who survived sudden cardiac death have increased risk of recurrent arrhythmias and death. J Cardiovasc Med (Hagerstown) 2010;11(11):810-14.

Bagdy G, Kecskemeti V, Riba P, Jakus R. Serotonin and epilepsy. J Neurochem 2007;100(4):857-73.

Bagnall RD, Crompton DE, Cutmore C, Regan BM, Berkovic SF, Scheffer IE, et al. Genetic analysis of PHOX2B in sudden unexpected death in epilepsy cases. Neurology 2014;83(11):1018-21.

Bagnall RD, Crompton DE, Petrovski S, Lam L, Cutmore C, Garry SI, Sadleir LG, Dibbens LM, Cairns A, Kivity S, Afawi Z, Regan BM, Duflou J, Berkovic SF, Scheffer IE, Semsarian C. Exome-based analysis of cardiac arrhythmia, respiratory control, and epilepsy genes in sudden unexpected death in epilepsy. Ann Neurol. 2016;79(4):522-34.

Bardai A, Blom MT, van Noord C, Verhamme KM, Sturkenboom MC, Tan HL. Sudden cardiac death is associated both with epilepsy and with use of antiepileptic medications. Heart 2014, Jul 16. Epub ahead of print.

Bardai A, Lamberts RJ, Blom MT, Spanjaart AM, Berdowski J, van der Staal SR, et al. Epilepsy is a risk factor for sudden cardiac arrest in the general population. PLoS One 2012;7(8):e42749.

Barraco RA, Janusz CA, Schoener EP, Simpson LL. Cardiorespiratory function is altered by picomole injections of 5'-N-ethylcarboxamidoadenosine into the nucleus tractus solitarius of rats. Brain Res 1990;507(2):234-46.

Barratt A, Wyer PC, Hatala R, McGinn T, Dans AL, Keitz S, et al. Tips for learners of evidence-based medicine: 1. relative risk reduction, absolute risk reduction and number needed to treat. Can Med Assoc J 2004;171:353–58.

Basheer R, Strecker RE, Thakkar MM, McCarley RW. Adenosine and sleep-wake regulation. Prog Neurobiol 2004;73:379-396.

Bateman LM, Li CS, Lin TC, Seyal M. Serotonin reuptake inhibitors are associated with reduced severity of ictal hypoxemia in medically refractory partial epilepsy. Epilepsia 2010;51(10):2211-14. 

Bateman LM, Li CS, Seyal M. Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors. Brain 2008;131(Pt 12):3239-45.

Bateman LM, Spitz M, Seyal M. Ictal hypoventilation contributes to cardiac arrhythmia and SUDEP: report on two deaths in video-EEG-monitored patients. Epilepsia 2010;51(5):916-20.

Battino D, Tomson T, Bonizzoni E, Craig J, Lindhout D, Sabers A, et al. Seizure control and treatment changes in pregnancy: observations from the EURAP epilepsy pregnancy registry. Epilepsia 2013:54:1621-27.

Bellon M, Panelli R, Rillotta F. Experiences and needs of people bereaved by epilepsy: results from an online Australian survey. Poster presented at 10th Asian and Oceanian Epilepsy Congress. 2014.

Benarroch EE. HCN channels: function and clinical implications. Neurology 2013;80:304-10.

Bender RA, Soleymani SV, Brewster AL, Nguyen ST, Beck H, Mathern GW, et al. Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus. J Neurosci 2003;23(17):6826-36.

Beniczky S. Detection of generalized tonic-clonic seizures by a wireless wrist accelerometer: A prospective, multicenter study. Epilepsia 2013, 54(4):e58-61.

Berg AT, Nickels K, Wirrell E, Geerts AT, Callenbach PM, Arts WF, et al. Mortality risks in new-onset childhood epilepsy. Pediatrics 2013;132:124-31.

Berthon-Jones M, Sullivan CE. Ventilation and arousal responses to hypercapnia in normal sleeping humans. J Appl Physiol 1984;57:59-67.

Bird JM, Dembny KAT, Sandeman D, Butler S. Sudden Unexplained Death in Epilepsy: An Intracranially Monitored Case. Epilepsia 1997;38:S52-S56.

Boison D. Adenosine kinase, epilepsy and stroke: mechanisms and therapies. Trends Pharmacol Sci 2006;27:652-658.

Boison D. Methylxanthines, seizures and excitotoxicity. Handb Exp Pharmacol 2010;200:251-66.

Boison D. Adenosine dysfunction in epilepsy. Glia 2012;60(8):1234–43.

Boison D. Adenosine and seizure termination: endogenous mechanisms. Epilepsy Curr 2013a;13(1):35-37.

Boison D. Adenosine kinase: exploitation for therapeutic gain. Pharma Rev 2013b;65:906-43.

Boison D, Chen JF, Fredholm BB. Adenosine signalling and function in glial cells. Cell Death Differ 2010;17:1071-82.

Boison D, Sandau US, Ruskin DN, Kawamura M Jr, Masino SA. Homeostatic control of brain function - new approaches to understand epileptogenesis. Front Cell Neurosci 2013;7:109.

Boison D, Scheurer L, Zumsteg V, Rülicke T, Litynski P, Fowler B, et al. Neonatal hepatic steatosis by disruption of the adenosine kinase gene. Proc Natl Acad Sci USA 2002;99(10):6985-90.

Booth C, Gaspar HB. Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID). Biologics 2009;3:349-58.

Bozorgi A, Lhatoo S. Seizures, cerebral shutdown and SUDEP. Epilepsy Curr 2013;13(5):236-240.

Brackenbury WJ, Yuan Y, O'Malley HA, Parent JM, Isom LL. Abnormal neuronal patterning occurs during early postnatal brain development of Scn1b-null mice and precedes hyperexcitability. Proc Natl Acad Sci USA 2013;110:1089-94.

Brennan TJ, Seeley WW, Kilgard M, Schreiner CE, Tecott LH. Sound-induced seizures in serotonin 5-HT2c receptor mutant mice. Nat Genet 1997;16(4):387-90.

Brigo F, Igwe SC, Ausserer H, Nardone R, Tezzon F, Bongiovanni LG, et al. Why do people Google epilepsy? An infodemiological study of online behavior for epilepsy-related search terms. Epilepsy Behav 2014;31:67-70.

Brodie MJ, Holmes GL. Should all patients be told about sudden unexpected death in epilepsy (SUDEP)? Pros and cons. Epilepsia 2008;49(Suppl 9):99-101.

Brown RE, Basheer R, McKenna JT, Strecker RE, McCarley RW. Control of sleep and wakefulness. Physiol Rev 2012;92:1087-1187.

Brown SW, Goldstein LH. Can seizure-alert dogs predict  seizures? Epilepsy Res 2011;97:236-42.

Brown S, Shankar R, Cox D, Jory C, Mclean B. Clinical governance: risk assessment in SUDEP. Clin Gov: an Int J 2013;18(4):325-31.

Brownstein CA, Goldstein RD, Thompson CH, Haynes RL, Giles E, Sheidley B, Bainbridge M, Haas EA, Mena OJ, Lucas J, Schaber B, Holm IA, George AL Jr, Kinney HC, Poduri AH. SCN1A variants associated with sudden infant death syndrome. Epilepsia 2018;59(4):e56-e62.

Buchanan GF. Timing, sleep and respiration in health and disease. Prog Mol Biol Transl Sci 12013;19:191-219.

Buchanan GF, Murray NM, Hajek MA, Richerson GB. Serotonin neurones have anti-convulsant effects and reduce seizure-induced mortality. Journal Physiol 2014;592(Pt 19):4395-410.

Buchanan GF, Richerson GB. Central serotonin neurons are required for arousal to CO2. Proc Natl Acad Sci USA 2010;107:16354-16359.

Buelow JM, Privitera M, Levisohn P, Barkley GL. A description of current practice in epilepsy monitoring units. Epilepsy Behav 2009;15(3):308-13.

Bulow K. Respiration and wakefulness in man. Acta Physiol Scand Suppl 1963;59:1-110.

Callenbach PM, Westendorp RG, Geerts AT, Arts WF, Peeters EA, van Donselaar CA, et al. Mortality risk in children with epilepsy: the Dutch study of epilepsy in childhood. Pediatrics 2001;107(6):1259-63.

Camfield P, Camfield C. Sudden unexpected death in people with epilepsy: a pediatric perspective. Semin Pediatr Neurol 2005;12(1):10-14.

Catcheside PG, Mohtar AA, Reynolds KJ. Airflow resistance and CO2 rebreathing properties of anti-asphyxia pillows designed for epilepsy.  Seizure 2014;23(6):462-67.

CDC - see Centers for Disease Control & Prevention.

Centers for Disease Control & Prevention (CDC) 2010. Comorbidity in adults with epilepsy--United States, 2010. MMWR Morb Mortal Wkly Rep 2013;62(43):849-53.

Centers for Disease Control and Prevention (CDC) ONLINE. Sudden Unexpected Infant Death and Sudden Infant Death Syndrome.

Centre for Maternal and Child Enquiries (CMACE). Saving mothers’ lives: reviewing maternal deaths to make motherhood safer: 2006–2008. The eighth report of the confidential enquiries into maternal deaths in the United Kingdom. BJOG 2011;118s1:1-203.

Chagoya de Sanchez V. Circadian variations of adenosine and of its metabolism. Could adenosine be a molecular oscillator for circadian rhythms? Can J Physiol Pharmacol 1995;73:339-355.

Chaila E, Bhangu J, Tirupathi S, Delanty N. Ictal bradycardia and asystole associated with intractable epilepsy: a case series. Br J Cardiol 201;17:245-48.

Chapman SCE, Horne R, Chater A, Hukins D, Smithson WH. Patients' perspectives on antiepileptic medication: relationships between beliefs about medicines and adherence among patients with epilepsy in UK primary care. Epilepsy Behav 2014;31(Feb):312-20.

Chen C, Westenbroek RE, Xu X, et al. Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. J Neurosci 2004;24:4030-42.

Cheah CS, Yu FH, Westenbroek RE, Kalume FK, Oakley JC, Potter GB, et al. Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome. Proc Natl Acad Sci USA 2012;109:14646–51.

Chinese Ministry of Health. Bulletin of Health Statistics in China 2005. Beijing: China Xiehe Medical University Press, 2005.

Clark RS, Carcillo JA, Kochanek PM, Obrist WD, Jackson EK, Mi Z, et al. Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humans. Neurosurg 1997;41:1284–92. Discussion 1292-93.

CMACE - see Centre for Maternal and Child Enquiries.

Commons KG. Ascending serotonin neuron diversity under two umbrellas. Brain Struct Funct 2016;221:3347-3360.

Coyle HP, Baker-Brian N, Brown SW. Coroner's autopsy reporting on sudden unexplained death in epilepsy (SUDEP) in the UK. Seizure 1994;3:247-254. 

Dasheiff RM. Sudden unexpected death in epilepsy: a series from an epilepsy surgery program and speculation on the relationship to sudden cardiac death. J Clin Neurophysiology: official publication of the American Electroencephalographic Society 1991;8(2):216-22.

Dasheiff RM, Dickinson LJ. Sudden unexpected death of epileptic patient due to cardiac arrhythmia after seizure. Arch Neurol 1986;43(2):194-96.

DeGiorgio CM, DeGiorgio AC. SUDEP and heart rate variability. Epilepsy Res 2010;90(3):309-10; author reply 311-12.

Delogu AB, Spinelli A, Battaglia D, Dravet C, De Nisco A, Saracino A, et al. Electrical and autonomic cardiac function in patients with Dravet syndrome. Epilepsia 2011;52(Suppl 2):55-58.

Department of Health (DOH). Annual report of the Chief Medical Officer of the Department of Health 2001: Epilepsy death in the shadows. UK: DOH; 2001.

Department of Psychiatry, Sichuan Medical School. Investigative report on the incidence of epilepsy in a population of 420,000 in Sichuan. Chin J Nerv Ment Dis 1981;14:135-38.

Devilat M, Gomez V, Mena F, Valenzuela B, Erazo R. Mortalidad en epilepsia en niños: la epilepsia en Latino-américa. I Congreso Latino Americano de Epilepsia. Santiago de Chile. OMS/OPS/ILAE/IBE. 2000.

Devinsky O. Sudden, unexpected death in epilepsy. N Engl J Med 2011;365(19):1801-11.

Devinsky O, Hesdorffer DC, Thurman DJ, Lhatoo S, Richerson G. Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention. Lancet Neurol 2016;15:1075-1088.

Diaz JA, Griffith RA, Ng JJ, Reinert SE, Friedmann PD, Moulton AW. Patients’ use of the internet for medical information. J Gen Intern Med 2002;17(March):180-85.

Di Gennaroemail G, Picardi A, Sparano A, Mascia A, Meldolesi GN, Grammaldo LG, et al. Seizure clusters and adverse events during pre-surgical video-EEG monitoring with a slow anti-epileptic drug (AED) taper. Clin Neurophysiol 2012;123:486-88.

Diógenes MJ, Neves-Tomé R, Fucile S, Martinello K, Scianni M, Theofilas P. Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase. Cereb Cortex 2014;24(1):67-80.

Ding D, Wang WZ, Wu JZ, Ma GY, Dai XY, Yang B, et al. Premature mortality in people with epilepsy in rural China: a prospective study. Lancet Neurology 2006;5:823-27.

Ding D, Wang W, Wu J, Yang H, Li S, Dai X, et al. Premature mortality risk in people with convulsive epilepsy: long follow-up of a cohort in rural China. Epilepsia 2013;54:512-17.

Dobesberger J, Walser G, Unterberger I, Seppi K, Kuchukhidze G, Larch J, et al. Video-EEG monitoring: safety and adverse events in 507 consecutive patients. Epilepsia 2011;52:443-52.

Dolgin E. Technology: dressed to detect. Nature 2014;511(7508):S16–S17.

Donner EJ, Buchhalter J. Commentary: It's time to talk about SUDEP. Epilepsia 2014;55(10):1501-3.

Donner EJ, Jeffs T, Jette N; Are Canadian paediatricians aware of SUDEP? (abstract); American Epilepsy Society Meeting 2012.

Donner EJ, Osland K, Leach JP, Waddell B, Duncan S, Nashef L, et al. The aftermath of SUDEP: lessons learned and the road forward. Epilepsia;57 (Suppl 1);46-53. 

Donner EJ, Smith CR, Snead OC 3rd. Sudden unexplained death in children with epilepsy. Neurology 2001;57(3):430-34.

Downs J, Bruine de Bruin W, Fischhoff B. Parents’ vaccination comprehension and decisions. Vaccine 2008;26:1595-1607.

Duff AJM. Determination of Sheriff Alistair Duff, Sheriff of Tayside Central and Fife at Dundee. Inquiry held under Fatal Accidents and Sudden Deaths Inquiry (Scotland) Act 1976 into the deaths of Erin Casey and Christina Fiorre Ilia. 2011.

Duncan S, Tonberg A, Harden J, McLellan A, Chin R; SUDEP disclosure in young adults with epilepsy: patients’ reaction, perception of risk, views on timing and behavioural change (abstract); American Epilepsy Society Meeting 2013.

Dunser MW & Hasibeder WR. Sympathetic overstimulation during critical illness: adverse effects of adrenergic stress. Journal of intensive care medicine 2009;24(5):293-316.

Durazzo TS, Spencer SS, Duckrow RB, Novotny EJ, Spencer DD, Zaveri HP. Temporal distributions of seizure occurrence from various epileptogenic regions. Neurology 2008;70:1265-1271.

During MJ, Spencer DD. Adenosine: a potential mediator of seizure arrest and postictal refractoriness. Ann Neurol 1992;32(5):618-24.

Eastaugh AJ, Thompson T, Vohra J, O’Brien TJ, Winship I. (submitted)

Edey S, Moran N, Nashef L. SUDEP and epilepsy-related mortality in pregnancy. Epilepsia. 2014;55(7):e72-4.

Elliott JO, Moore JL, Lu B. Health status and behavioral risk factors among persons with epilepsy in Ohio based on the 2006 Behavioral Risk Factor Surveillance System. Epilepsy Behav 2008;12(3):434-44.

Espinosa PS, Lee JW, Tedrow UB, Bromfield EB, Dworetzky BA. Sudden unexpected near death in epilepsy: malignant arrhythmia from a partial seizure. Neurology 2009;72(19):1702-3.

Etherington LV, Graham E, Patterson GE, Meechan L, Boison D, Irving AJ, et al. Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus. Neuropharma 2009;56(2):429-37.

Ettinger AB, Good MB, Manjunath R, Faught RE, Bancroft T. The relationship of depression to antiepileptic drug adherence and quality of life in epilepsy. Epilepsy Behav 2014;36:138-43.

Evans DB, Schenden JA, Bristol JA. Adenosine receptors mediating cardiac depression. Life Sci 1982;31(22):2425-32.

Fazel S, Wolf A, Långström N, Newton CR, Lichtenstein P. Premature mortality in epilepsy and the role of psychiatric comorbidity: a total population study. The Lancet 2013;382(9905):1646-54.

Faingold CL, Kommajosyula SP, Long X, Plath K, Randall M. Serotonin and sudden death: differential effects of serotonergic drugs on seizure-induced respiratory arrest in DBA/1 mice. Epilepsy Behav 2014;37:198-203.

Faingold CL, Randall M. Effects of age, sex, and sertraline administration on seizure-induced respiratory arrest in the DBA/1 mouse model of sudden unexpected death in epilepsy (SUDEP). Epilepsy Behav 2013;28:78-82.

Faingold CL, Randall M, Mhaskar Y, Uteshev VV. Differences in serotonin receptor expression in the brainstem may explain the differential ability of a serotonin agonist to block seizure-induced sudden death in DBA/2 vs. DBA/1 mice. Brain Res 2011;1418:104-10.

Faingold CL, Tupal S, Randall M. Prevention of seizure-induced sudden death in a chronic SUDEP model by semichronic administration of a selective serotonin reuptake inhibitor. Epilepsy Behav 2011;22:186-190.

Fairgrieve SD, Jackson M, Jonas P, Walshaw D, White K, Montgomery TL, et al. Population based, prospective study of the care of women with epilepsy in pregnancy. BMJ 2000;321:7262.

Faught E, Duh MS, Weiner JR, Guerin A, Cunnington MC. Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM Study. Neurology 2008;71:1572-78.

Fedele DE, Li T, Lan JQ, Fredholm BB, Boison D. Adenosine A1 receptors are crucial in keeping an epileptic focus localized. Exp Neurol 2006;200(1):184-190.

Ficker DM, So EL, Shen WK, Annegers JF, O’Brien PC, Cascino GD, et al. Population-based study of the incidence of sudden unexplained death in epilepsy. Neurology 1998; 51:1270-74.

Fisher R, Salanova V, Witt T, Worth R, Henry T, Gross R, et al. Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia 2010;51:899–908.

Friedman D, Donner EJ, Stephens D, Wright C, Devinsky O. Sudden unexpected death in epilepsy: knowledge and experience among US and Canadian neurologists. Epilepsy Behav 2014;35C:13-18.

Fukuda M, Suzuki Y, Hino H, Morimoto T, Ishii E. Activation of central adenosine A(2A) receptors lowers the seizure threshold of hyperthermia-induced seizure in childhood rats. Seizure 2011;20:156-59.

Gaitatzis A, Carroll K, Majeed A, Sander JW. The epidemiology of the comorbidity of epilepsy in the general population. Epilepsia 2004;45(12):1613-22.

Gaitatzis A, Purcell B, Carroll K, Sander JWAS, Majeed A. Differences in the use of health services among people with and without epilepsy in the United Kingdom: socio-economic and disease-specific determinants. Epilepsy Research 2002;50(3):233-241.

Gayatri NA, Morrall MC, Jain V, Kashyape P, Pysden K, Ferrie C. Parental and physician beliefs regarding the provision and content of written sudden unexpected death in epilepsy (SUDEP) information. Epilepsia 2010;51:777–82.

Geertsema EE, Thijs RD, Gutter T, Vledder B, Arends JB, Leijten FS, Visser GH, Kalitzin SN. Automated video-based detection of nocturnal convulsive seizures in a residential care setting. Epilepsia 2018 Jun;59 Suppl 1:53-60.

Genton P, Velizarova R, Dravet C. Dravet syndrome: the long-term outcome. Epilepsia 2011;52(Suppl 2):44-49.

George JR, Davis GG. Comparison of anti-epileptic drug levels in different cases of sudden death. J Forensic Sci 1998; 43:598-603.

Gheyara AL, Ponnusamy R, Djukic B, Craft RJ, Ho K, Guo W, et al. Tau reduction prevents disease in a mouse model of Dravet syndrome. Ann Neurol 2014;76(3):443-56.

Glasscock E, Qian J, Yoo JW, Noebels JL. Masking epilepsy by combining two epilepsy genes. Nature Neurosci 2007;10:1554-58.

Glasscock E, Yoo JW, Chen TT, Klassen TL, Noebels JL. Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy. J Neurosci 2010;30:5167-75.

Goldman AM, Glasscock E, Yoo J, Chen TT, Klassen TL, Noebels JL. Arrhythmia in heart and brain: KCNQ1 mutations link epilepsy and sudden unexplained death. Sci Transl Med 2009;1:2ra6.

Gouder N, Fritschy JM, Boison D. Seizure suppression by adenosine A1 receptor activation in a mouse model of pharmacoresistant epilepsy. Epilepsia 2003;44(7):877-85.

Gouder N, Scheurer L, Fritschy J-M, Boison D. Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis. J Neurosci 2004;24(3):692-701.

Hajek MA, Buchanan GF. Influence of vigilance state on physiologic consequences of seizures and seizure-induced death in mice. J Neurophysiol 2016;115:2286-2293.

Hamilton W, Green T, Martins T, Elliott K, Rubin G, Macleod U. Evaluation of risk assessment tools for suspected cancer in general practice: a cohort study. Brit J Gen Pract 2013;63(606):e30-e36

Hanna NJ, Black M, Sander JW, Smithson WH, Appleton R, Brown S, et al. The national sentinel clinical audit of epilepsy-related death. London: The Stationary Office, 2002.

Hanna J, Wannamaker BB. Judicial reports on avoidable deaths. Global Conversation 2014.

Harden J, Tonberg A, Chin RF, McLellan A, Duncan S. If you're gonna die, you're gonna die: young adults' perceptions of sudden unexpected death in epilepsy. Chronic Illness 2014. Published online before print October 31, 2014.

Harper A. How can we improve the care of pregnant women with epilepsy? MSc dissertation 2012, King’s College London.

Hartmann HA, Colom LV, Sutherland ML, Noebels JL. Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain. Nature Neuro 1999;2:593-95.

Hawkins NA, Martin MS, Frankel WN, Kearney JA, Escayg A. Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus. Neurobiol Dis 2011;41(3):655-60.

Herlenius E, Lagercrantz H, Yamamoto Y. Adenosine modulates inspiratory neurons and the respiratory pattern in the brainstem of neonatal rats. Pediatr Res 1997;42(1):46-53.

Heron SE, Hernandez M, Edwards C, Edkins E, Jansen FE, Scheffer IE , et al. Neonatal seizures and long QT syndrome: a cardiocerebral channelopathy? Epilepsia 2010;51(2):293-96.

Hershfield MS. PEG-ADA replacement therapy for adenosine deaminase deficiency: an update after 8.5 years. Clin Immunol Immunopathol 1995;76(3 Pt 2):S228-32.

Hesdorffer DC, Tomson T. Adjunctive antiepileptic drug therapy and prevention of SUDEP. Lancet Neurol 2011;10(11):948-9.

Hesdorffer DC, Tomson T, Benn E, Sander JW, Nilsson L, Langan Y, et al. Combined analysis of risk factors for SUDEP. Epilepsia 2011;52(6):1150-59.

Hesdorffer DC, Tomson T, Benn E, Sander JW, Nilsson L, Langan Y, et al. and for the ILAE Commission on Epidemiology; Subcommission on Mortality. Do antiepileptic drugs or generalized tonic-clonic seizure frequency increase SUDEP risk? A combined analysis. Epilepsia 2012;53:249-52.

Hill K, Lopez AD, Shibuya K, Jha P; Monitoring of Vital Events (MoVE). Interim measures for meeting needs for health sector data: births, deaths, and causes of death. Lancet 2007;370(9600):1726-35.

Hindocha N, Nashef L, Elmslie F, Birch R, Zuberi S, Al-Chalabi A, et al. Two cases of sudden unexpected death in epilepsy in a GEFS+ family with an SCN1A mutation. Epilepsia 2008;49:360-65.

Hirsch LJ, Donner EJ, So EL, Jacobs M, Nashef L, Noebels JL, et al. Abbreviated report of the NIH/NINDS workshop on sudden unexpected death in epilepsy. Neurology 2011;76:22:1932-38.

Hodges MR, Wehner M, Aungst J, Smith JC, Richerson GB. Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development. J Neurosci 2009;29:10341-49.

Holst A, Winkel B, Risgaard B, Nielsen JB, Rasmussen PV, Haunso S, et al. Epilepsy and risk of sudden unexpected death in the young: a nationwide study. Epilepsia  2013;54:1613-20.

Holth JK, Bomben VC, Reed JG, Inoue T, Younkin L, Younkin SG, et al. Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy. J Neurosci 2013;33(4):1651-59.

Huberfeld G, Blauwblomme T, Miles R. Hippocampus and epilepsy: Findings from human tissues. Rev Neurol (Paris) 2015;171:236-251.

Hunt CE, Brouillette RT. Sudden infant death syndrome: 1987 perspective. J Pediatr 1987;110:669-678.

Institute of Medicine (IOM). Epilepsy across the spectrum: promoting health and understanding. Washington, DC: The National Academies Press. 2012.

Janszky I, Hallqvist J, Tomson T, Ahlbom A, Mukamal KJ, Ahnve S. Increased risk and worse prognosis of myocardial infarction in patients with prior hospitalization for epilepsy--the Stockholm Heart Epidemiology Program. Brain 2009;132(Pt 10):2798-804.

Jeppesen J, Fuglsang-Frederiksen A, Brugada R, Pedersen B, Rubboli G, Johansen P, et al. Heart rate variability analysis indicates preictal parasympathetic overdrive preceding seizure-induced cardiac dysrhythmias leading to sudden unexpected death in a patient with epilepsy. Epilepsia 2014;55(7):e67-71.

Johnson JN, Hofman N, Haglund CM, Cascino GD, Wilde AA, Ackerman MJ. Identification of a possible pathogenic link between congenital long QT syndrome and epilepsy. Neurology 2009;72:224-31.

Johnson JN, Tester DJ, Bass NE, Ackerman MJ. Cardiac channel molecular autopsy for sudden unexpected death in epilepsy. J Child Neurol 2010;25:916-21.

Kalume F, Westenbroek RE, Cheah CS, Yu FH, Oakley JC, Scheuer T, et al. Sudden unexpected death in a mouse model of Dravet syndrome. J Clin Invest 2013;123(4):1798-808.

Kang JY, Rabiei AH, Myint L, Nei M. Equivocal significance of post-ictal generalized EEG suppression as a marker of SUDEP risk. Seizure 2017;48:28-32.

Kanner AM. Depression and epilepsy: a review of multiple facets of their close relation. Neurol Clin 2009;27(4):865-80.

Kappoor D, Wallace S. Trends in maternal deaths from epilepsy in the United Kingdom: a 30-year retrospective review. Obstet Med 2014;7(4):160-64.

Kerr M, Thomson R, Linehan C, Glynn M, Mula M, Gil-Nagel A et al. Listening for a change: medical and social needs of people with epilepsy and intellectual disability. A Joint Report of the International League Against Epilepsy Task Force on Intellectual Disability and the International Bureau for Epilepsy. 2014.

Kim Y, Bolortuya Y, Chen L, Basheer R, McCarley RW, Strecker RE. Decoupling of sleepiness from sleep time and intensity during chronic sleep restriction: evidence for a role of the adenosine system. Sleep 2012;35(6):861-69.

Kim Y, Bravo E, Thirnbeck CK, Smith-Mellecker LA, Kim SH, Gehlbach BK, Laux LC, Zhou X, Nordli DR Jr, Richerson GB. Severe peri-ictal respiratory dysfunction is common in Dravet syndrome. Journal of Clinical Investigation. 2018; Mar 1;128(3):1141-1153.

Kinney HC, McDonald AG, Minter ME, Berry GT, Poduri A, Goldstein RD. Witnessed sleep-related seizure and sudden unexpected death in infancy: a case report. Forensic Sci Med Pathol 2013;9(3):418-21.

Kinney HC, Richerson GB, Dymecki SM, Darnall RA, Nattie EE. The brainstem and serotonin in the sudden infant death syndrome. Annu Rev Pathol 2009;4:517-50.

Klassen TL, Bomben VC, Patel A, Drabek J, Chen TT, Gu W, et al. High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile. Epilepsia 2014;55(2):e6-12.

Kroner BL, Wright C, Friedman D, Macher K, Preiss L, Misajon J, et al. Characteristics of epilepsy patients and caregivers who either have or have not heard of SUDEP. Epilepsia 2014;55(10):1486-94.

Kuisle M, Wanaverbecq N, Brewster AL, Frere SG, Pinault D, Baram TZ, et al. Functional stabilization of weakened thalamic pacemaker channel regulation in rat absence epilepsy. J Physiol 2006;575(Pt 1):83-100.

Kuo J, Zhao W, Li CS, Kennedy JD, Seyal M. Postictal immobility and generalized EEG suppression are associated with the severity of respiratory dysfunction. Epilepsia 2016;57:412-417.

Lacuey N, Zonjy B, Hampson JP, Rani MRS, Zaremba A, Sainju RK, Gehlbach BK, Schuele S, Friedman D, Devinsky O, Nei M, Harper RM, Allen L, Diehl B, Millichap JJ, Bateman L, Granner MA, Dragon DN, Richerson GB, Lhatoo SD. The incidence and significance of periictal apnea in epileptic seizures. Epilepsia 2018;Mar;59(3):573-582.

Lado FA, Moshe SL. How do seizures stop? Epilepsia 2008;49(10):1651-64.

Lamberts RJ, Blom MT, Novy J, Belluzzo M, Seldenrijk A, Penninx BW, et al. Increased prevalence of ECG markers for sudden cardiac arrest in refractory epilepsy. J Neurol Neurosurg Psychiatry 2014.

Lamberts RJ, Blom MT, Wassenaar M, Bardai A, Leijten FSS, de Haan GJ, et al. Sudden cardiac arrest in people with epilepsy in the community: circumstances and risk factors. Forthcoming.

Lamberts RJ, Tan HL, Leijten QH, Sander JW, Thijs RD [Sudden unexpected death in epilepsy: SUDEP]. Ned Tijdschr Geneeskd 2013;157(48):A6193.

Lamberts RJ, Thijs RD, Laffan A, Langan Y, Sander JW. Sudden unexpected death in epilepsy: people with nocturnal seizures may be at highest risk. Epilepsia 2012;53(2):253-57.

Langan Y, Nashef L, Sander JW. Case-control study of SUDEP. Neurology 2005;64(7):1131-33.

Langan Y, Nolan N, Hutchinson M. The incidence of sudden unexpected death in epilepsy (SUDEP) in South Dublin and Wicklow. Seizure 1998;7:355-8.

Lanz M, Oehl B, Brandt A, Schulze-Bonhage A. Seizure induced cardiac asystole in epilepsy patients undergoing long term video-EEG monitoring. Seizure 2011;20(2):167-72.

Lathers CM, Leestma JE, Schachter SC, Koehler SA, Claycamp HG, Wannamaker BB, et al. Chapter 5. Forensic SUDEP Cluster Risk Factor Identifier Method. In Lathers CM, Schraeder PL, Leestma JE, Wannamaker BB, Verrier RL, Schachter SC, editors. Sudden death in epilepsy. New method for analyzing risk. Boca Raton, FL: CRC Press, Taylor and Francis Group; Forthcoming 2015.

Lathers CM, Schraeder PL. Verbal autopsies and SUDEP. Epilepsy and Behav 2009;14:573-6.

Lazarus M, Chen JF, Huang ZL, Urade Y, Fredholm BB. Adenosine and Sleep. Handb Exp Pharmacol 2017 Jun 24.

Leach JP. SUDEP discussions with patients and families. Pract Neurol 2012;12(2):103-6.

Lear-Kaul KC, Coughlin L, Dobersen MJ. Sudden unexpected death in epilepsy: a retrospective study. Am J Forensic Med Pathol 2005;26:11-17.

Leestma JE. Forensic considerations and sudden death in epilepsy. In: Lathers CM, Schraeder PL, Bungo MW, Leestma JE. Sudden death in epilepsy: forensic and clinical issues. Boca Raton: CRC Press. 2011;37-55.

Leestma JE, Walczak T, Hughes JR, Kalelkar MB, Teas SS. A prospective study on sudden unexpected death in epilepsy. Ann Neurol 1989;26:195-203.

Le Gal F, Korff CM, Monso-Hinard C, Mund MT, Morris M, Malafosse A, et al. A case of SUDEP in a patient with Dravet syndrome with SCN1A mutation. Epilepsia 2010;51:1915-18.

Lende van der M, Surges R, Sander JW, Thijs RD. Cardiac arrhythmias during epileptic seizures: a review. Forthcoming.

Lerner JS, Keltner D. Fear, Anger, Risk. J Personal Soc Psychol 2001;81(1):146-59.

Lewis S, Higgin S, Goodwin M. Informing patients about sudden unexpected death in epilepsy: a survey of specialist nurses. Brit J Neuro Nursing 2008;4:30-34.

Lhatoo SD, Faulkner HJ, Dembny K, Trippick K, Johnson C, Bird JM. An electroclinical case-control study of sudden unexpected death in epilepsy. Ann Neurol 2010;68(6):787-96.

Lhatoo SD, Sander JW. Cause-specific mortality in epilepsy. Epilepsia 2005;46(Suppl 11):36-9.

Linsell CR, Lightman SL, Mullen PE, Brown MJ, Causon RC. Circadian rhythms of epinephrine and norepinephrine in man. J Clin Endocrinol Metab 1985;60:1210-1215.

Li SC, Cheng XM, Wang WZ, Wu SP, Feng EJ, Jiang GX, et al. Epidemiologic study of central nerve system diseases in rural China. Chin J Neurosurg 1989;5:2-6.

Li SC, Schoenberg BS, Wang CC, Cheng XM, Zhou SS, Bolis CL. Epidemiology of epilepsy in urban areas of the People’s Republic of China. Epilepsia 1985;26:391-94.

Liebrechts-Akkerman G, Liu F, Lao Grueso O, Ooms AHAG, van Duijn K, Vermeulen M, et al. PHOX2B polyalanine repeat length is associated with sudden infant death syndrome and unclassified sudden infant death in the Dutch population. Int J Legal Med 2014;128(4):621-29.

Loddenkemper T, Lockley SW, Kaleyias J, Kothare SV. Chronobiology of epilepsy: diagnostic and therapeutic implications of chrono-epileptology. J Clin Neurophysiol 2011;28:146-153.

Lopez-Santiago LF, Meadows LS, Ernst SJ, Chen C, Malhotra JD, McEwen DP, et al. Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. J Mol Cell Cardiol 2007;43(5):636-47.

Lotufo PA, Valiengo L, Bensenor IM, Brunoni AR. A systematic review and meta-analysis of heart rate variability in epilepsy and antiepileptic drugs. Epilepsia 2012;53:272-82.

Lusardi TA, Lytle NK, Szybala C, Boison D. Caffeine prevents acute mortality after TBI in rats without increased morbidity. Exp Neurol 2012;234(1):161-68.

Massey CA, Sowers LP, Dlouhy BJ, Richerson GB. Mechanisms of sudden unexpected death in epilepsy: the pathway to prevention. Nat Rev Neurol 2014;10(5):271-82.

Matos G, Scorza F, Mazzotti  DR, Guindalini C, Cavalheiro EA, Tufik S, Andersen ML. The effects of sleep deprivation on microRNA expression in rats submitted to pilocarpine-induced status epilepticus. Prog Neuropsych Biol Psych 2014;3(51):159-165.

Miller JW, Turner GM, Gray BC. Anticonvulsant effects of the experimental induction of hippocampal theta activity. Epilepsy Res 1994;18:195-204.

Miller WR, Young N, Friedman D, Buelow JM, Devinsky O. Discussing sudden unexpected death in epilepsy (SUDEP) with patients: practices of health-care providers. Epilepsy Behav 2014;32:38-41.

Mitchell HA, Weinshenker D. Good night and good luck: norepinephrine in sleep pharmacology. Biochem Pharmacol 2010;79:801-809.

Mittan RJ. How to discuss SUDEP with patients and families. The Epilepsy Report, Epilepsy Australia 2010;(2):10-11.

Molnar J, Zhang F, Weiss J, Ehlert FA, Rosenthal JE. Diurnal pattern of QTc interval: how long is prolonged? Possible relation to circadian triggers of cardiovascular events. J Am Coll Cardiol 1996;27:76-83.

Monti JM. Serotonin control of sleep-wake behavior. Sleep Med Rev 2011 Aug;15(4):269-81.

Moore BM, Jerry JC, Tatalovic M, Kaufman ES, Kline DD, Kunze DL. The Kv1.1 null mouse, a model of sudden unexpected death in epilepsy (SUDEP). Epilepsia 2014;55:1808-1816.

Morrell MJ. Responsive cortical stimulation for the treatment of medically intractable partial epilepsy. Neurology 2011;77:1295–1304.

Morton B, Richardson A, Duncan S. Sudden unexpected death in epilepsy (SUDEP): don’t ask, don’t tell? J Neurol Neurosurg Psychiatry 2006;77:199-202.

Moseley BD, Wirrell EC, Nickels K, Johnson JN, Ackerman MJ, Britton J. Electrocardiographic and oximetric changes during partial complex and generalized seizures. Epilepsy Res 2011;95(3):237-45.

Mu J, Liu L, Zhang Q, Si Y, Hu J, Fang J, et al. Causes of death among people with convulsive epilepsy in rural West China: a prospective study. Neurology 2011;77:132-37

Murugesan A, Rani MRS, Hampson J, Zonjy B, Lacuey N, Faingold CL, Friedman D, Devinsky O, Sainju RK, Schuele S, Diehl B, Nei M, Harper RM, Bateman LM, Richerson G, Lhatoo SD. Serum serotonin levels in patients with epileptic seizures. Epilepsia 2018;Jun;59(6):e91-e97.

Naggar I, Lazar J, Kamran H, Orman R, Stewart M. Relation of autonomic and cardiac abnormalities to ventricular fibrillation in a rat model of epilepsy. Epilepsy Res 2014;108:44-56.

Nashef L. Sudden unexpected death in epilepsy: terminology and definitions. Epilepsia 1997;38(Suppl 11):6-8.

Nashef L, Fish DR, Garner S, Sander JW, Shorvon SD. Sudden death in epilepsy: a study of incidence in a young cohort with epilepsy and learning difficulty. Epilepsia 1995;36:1187-1194.

Nashef L, Garner S, Sander JW, Fish DR, Shorvon SD. Circumstances of death in sudden death in epilepsy: interviews of bereaved relatives. J Neurol Neurosurg Psychiatry 1998;64(3):349-52.

Nashef L, Walker F, Allen P, Sander JW, Shorvon SD, Fish DR. Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy. J Neurol Neurosurg Psychiatry 1996;60(3):297-300.

Nashef L, So EL, Ryvlin P, Tomson T. Unifying the definitions of sudden unexpected death in epilepsy. Epilepsia 2012;53(2):227-33. 

Nei M, Ho RT, Abou-Khalil BW, Drislane FW, Liporace J, Romeo A, Sperling MR. EEG and ECG in sudden unexplained death in epilepsy. Epilepsia. 2004;45(4):338-45.

Nei M, Ho RT, Sperling MR. EKG abnormalities during partial seizures in refractory epilepsy. Epilepsia 2000;41: 542–548

Nei M, Sperling MR, Mintzer S, Ho RT. Long-term cardiac rhythm and repolarization abnormalities in refractory focal and generalized epilepsy. Epilepsia 2012;53(8):e137-40.

Neligan A, Bell GS, Johnson AL, Goodridge DM, Shorvon SD, Sander JW. The long-term risk of premature mortality in people with epilepsy. Brain 2011;134(Pt 2):388-95.

Neufeld MY, Vishne T, Chistik V, Korczyn AD. Life-long history of injuries related to seizures. Epilepsy Res 1999;34(2-3):123-27

Ng M, Pavlova M. Why are seizures rare in rapid eye movement sleep? Review of the frequency of seizures in different sleep stages. Epilepsy Res Treat 2013:932790.

Ngugi AK, Bottomley C, Fegan G, Chengo E, Odhiambo R, Bauni E et al. Premature mortality in active convulsive epilepsy in rural Kenya: causes and associated factors. Neurology. 2014 Feb 18;82(7):582-9. 

NICE CG137 [National Institute for Health and Care Excellence (NICE) National Clinical Guideline (CG) 137]. Epilepsies: diagnosis and management. CG137. London: NICE; 2012.

Nicholas JM, Ridsdale L, Richardson MP, Ashworth M, Gulliford MC. Trends in antiepileptic drug utilisation in UK primary care 1993–2008: cohort study using the general practice research database. Seizure 2012;21(6):466-70.

Nicholas JM, Ridsdale L, Richardson MP, Grieve AP, Gulliford MC. Fracture risk with use of liver enzyme inducing antiepileptic drugs in people with active epilepsy: cohort study using the general practice research database. Seizure 2013;22(1):37-42.

Nickels KC, Grossardt BR, Wirrell EC. Epilepsy related mortality is low in children: a 30-year population-based study in Olmsted County, MN. Epilepsia 2012;53:2164-71.

Nilsson L, Farahmand BY, Persson PG, Thiblin I, Tomson T. Risk factors for sudden unexpected death in epilepsy: a case-control study. Lancet 1999;353:888-93.

Nobili L, Proserpio P, Rubboli G, Montano N, Didato G, Tassinari CA. Sudden unexpected death in epilepsy (SUDEP) and sleep. Sleep Med Rev 2011;15(4):237–46.

Noble AJ, McCrone P, Seed PT, Goldstein LH, Ridsdale L. Clinical-and cost-effectiveness of a nurse led self-management intervention to reduce emergency visits by people with epilepsy. PloS One 2014;9(3):e90789.

Noe KH, Drazkowski JF. Safety of long-term video-electroencephalographic monitoring for evaluation of epilepsy. Mayo Clin Proc 2009;84:495-500.

Nuñez L. Mexico. In: Chapman D, Panelli R, Hanna J, Jeffs T eds 2011. Sudden unexpected death in epilepsy: continuing the global conversation. Epilepsy Australia, Epilepsy Bereaved, SUDEP Aware. Camberwell. Australia. 2011:132-34.

O'Brien JE, Meisler MH. Sodium channel SCN8A (Nav1.6): properties and de novo mutations in epileptic encephalopathy and intellectual disability. Front Genet 2013;4:213.

Opeskin K, Berkovic SF. Risk factors for sudden unexpected death in epilepsy: a controlled prospective study based on coroners cases. Seizure 2003;12:456-64.

Opeskin K, Burke MP, Cordner SM, Berkovic SF. Comparison of antiepileptic drug levels in sudden unexpected death in epilepsy with death from other causes. Epilepsia 1999;40:1795-98.

Opeskin K, Harvey AS, Cordner SM, Berkovic SF. Sudden unexpected death in epilepsy in Victoria. J Clin Neurosci 2000;7:34-7.

Organización Panamericana de la Salud. Estrategia y Plan de Acción sobre Epilepsia. Washington. 2011.

Ostler A, Cousins S, Ridsdale L. The causes of death in epilepsy: a systematic review. Poster presentation at the Royal College of General Practitioner’s Annual Primary Care Conference. Liverpool 2nd October 2014.

Page A, Tobias M, Glover J, Wright C, Hetzel, D. Fisher E. Australian and New Zealand atlas of avoidable mortality. Adelaide: University of Adelaide; 2006.

Panelli R, Smithson H, Hanna J. Providing Information about SUDEP: the benefits and challenges. In Lathers CM, Schraeder PL, Leestma JE, Wannamaker RL, Verrier RL, Schachter SC, editors. Sudden death in epilepsy: new method for analysing risk. Boca Raton: CRC Press, Taylor and Francis Group; 2015.

Pearson, P, Steven A, Howe A, Sheikh A, Ashcroft D, Smith, P. Learning about patient safety: organisational context and culture in the education of healthcare professionals. J Health Serv Res Pol 2010;15(Suppl 1):4-10.

Pedley TA, Hauser WA. Sudden death in epilepsy: a wake-up call for management. Lancet 2002;359(9320):1790-1.

Peever JH, Stephenson R. Day-night differences in the respiratory response to hypercapnia in awake adult rats. Respir Physiol 1997;109:241-248.

Peng W, Danison JL, Seyal M. Postictal generalized EEG suppression and respiratory dysfunction following generalized tonic-clonic seizures in sleep and wakefulness. Epilepsia 2017;58:1409-1414.

Petrucci AN, Joyal KG, Buchanan GF. Effect of dorsal raphe serotonin neuron stimulation on post-ictal EEG suppression and arousal in mice. 2018 (in press)

Piccione G, Grasso F, Giudice E. Circadian rhythm in the cardiovascular system of domestic animals. Res Vet Sci 2005;79:155-160.

Pignatelli M, Beyeler A, Leinekugel X. Neural circuits underlying the generation of theta oscillations. J Physiol Paris 2012;106:81-92.​

Plug I, Hoffmann R, Mackenbach J. editors. Final Report. Avoidable mortality In the European Union: towards better indicators for the effectiveness of health systems. AMIEHS. Rotterdam: Erasmus Medical Center Rotterdam; 2011.

Poh MZ, Loddenkemper T, Reinsberger C, Swenson NC, Goyal S, Sabtala MC, et al. Convulsive seizure detection using a wrist-worn electrodermal activity and accelerometry biosensor. Epilepsia 2012;53:e93–e97.

Poncet L, Denoroy L, Jouvet M. Daily variations in in vivo tryptophan hydroxylation and in the contents of serotonin and 5-hydroxyindoleacetic acid in discrete brain areas of the rat. J Neural Transm Gen Sect 1993;92:137-150.

Porkka-Heiskanen T, Kalinchuk AV. Adenosine, energy metabolism and sleep homeostasis. Sleep Med Rev 2011;15(2):123-35.

Powell KL, Jones NC, Kennard JT, Ng C, Urmaliya V, Lau S, et al. HCN channelopathy and cardiac electrophysiologic dysfunction in genetic and acquired rat epilepsy models. Epilepsia 2014;55(4):609-20.

Powell KL, Ng C, O'Brien TJ, Xu SH, Williams DA, Foote SJ, et al. Decreases in HCN mRNA expression in the hippocampus after kindling and status epilepticus in adult rats. Epilepsia 2008;49(10):1686-95.

Puranik R, Chow CK, Duflou JA, Kilborn MJ, McGuire MA. Sudden death in the young. Heart Rhythm 2005;2(12):1277-82.

Purnell BS, Hajek MA, Buchanan GF. Time-of-day influences on respiratory sequelae following maximal electroshock-induced seizures in mice. J Neurophysiol 2017;118:2592-2600.

Purves SJ, Wilson-Young M, Sweeney VP. Sudden death in epilepsy: single case report with video-EEG documentation.  Epilepsia 1992;33(Suppl 3):123.

Qi Y, Wang J, Bomben VC, Li DP, Chen SR, Sun H, et al. Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death. Neuron 2014;83(5):1159-71.

Quigg M, Straume M, Menaker M, Bertram EH 3rd. Temporal distribution of partial seizures: comparison of an animal model with human partial epilepsy. Ann Neurol 1998;43:748-755.

Quigley MA, Chandramohan D, Rodriques LC. Diagnostic accuracy of physician review, expert algorithms and data-derived algorithms in adult verbal autopsies. Int J Epidemiol 1999;28:1081-7.

RamachandranNair R. What families want to know. Epilepsy Curr 2013;13(2):16.

RamachandranNair R, Jack SM. SUDEP: To discuss or not? Recommendations and experiences from bereaved relatives. American Epilepsy Society Annual Meeting 2013;Abst 3.319.

RamachandranNair R, Jack SM, Madhava AR, Shapiro MJ. SUDEP: What do patients want to know. American Epilepsy Society Annual Meeting 2014;Abst 2.065.

RamachandranNair R, Jack SM, Meaney BF, Ronen GM. SUDEP: what do parents want to know? Epilepsy Behav 2013;29(3):560-64.

Rauscher G, DeGiorgio AC, Miller PR, DeGiorgio CM. Sudden unexpected death in epilepsy associated with progressive deterioration in heart rate variability. Epilepsy Behav 2011;21:103-5.

RCPath - see Royal College of Pathologists.

RCPCH - see Royal College of Paediatrics and Child Health.

Reisinger TL, Newman M, Loring DW, Pennell PB, Meador KJ. Antiepileptic drug clearance and seizure frequency during pregnancy in women with epilepsy. Epilepsy & Behav 2013: 29:13-18.

Rheims S, Ryvlin P. Patients' safety in the epilepsy monitoring unit: time for revising practices. Curr Opin Neurol 2014;27:213-18.

Richerson GB. Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat Rev Neurosci 2004;5(6):449-61.